3,142 research outputs found

    Cúpula extensible

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    Reducing the complexity of a multiview H.264/AVC and HEVC hybrid architecture

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    With the advent of 3D displays, an efficient encoder is required to compress the video information needed by them. Moreover, for gradual market acceptance of this new technology, it is advisable to offer backward compatibility with existing devices. Thus, a multiview H.264/Advance Video Coding (AVC) and High Efficiency Video Coding (HEVC) hybrid architecture was proposed in the standardization process of HEVC. However, it requires long encoding times due to the use of HEVC. With the aim of tackling this problem, this paper presents an algorithm that reduces the complexity of this hybrid architecture by reducing the encoding complexity of the HEVC views. By using Na < ve-Bayes classifiers, the proposed technique exploits the information gathered in the encoding of the H.264/AVC view to make decisions on the splitting of coding units in HEVC side views. Given the novelty of the proposal, the only similar work found in the literature is an unoptimized version of the algorithm presented here. Experimental results show that the proposed algorithm can achieve a good tradeoff between coding efficiency and complexity

    Use of nano-additions to improve the performance of UHPFRCs used in geothermal power plant infrastructures

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    he interest of scientific community on application of nano-additions in concrete is continuously growing due to their outstanding physical and chemical properties. These nano-additions are usually added into concrete to increase the durability in aggressive environments, such as XA environmental exposure classes. This work shows preliminary results on the use of nano-additions in an Ultra High Performance Fiber-Reinforced Concrete (UHPFRC) used as a reference. This reference UHPFRC has been modified adding three types of nano-additions: alumina nanofibers (0.25% by weight of cement), cellulose nanocrystals (0.15% by weight of cement) and cellulose nanofibrils (0.15% by weight of cement). The influence of the nano-additions has been analyzed in terms of mechanical properties, such as flexural and compressive strength and on shrinkage and durability properties, analyzed by means of sorptivity tests on uncracked, cracked and self-healed specimens

    Astrocytes and Müller Cell Alterations During Retinal Degeneration in a Transgenic Rat Model of Retinitis Pigmentosa

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    Purpose: Retinitis pigmentosa includes a group of progressive retinal degenerative diseases that affect the structure and function of photoreceptors. Secondarily to the loss of photoreceptors, there is a reduction in retinal vascularization, which seems to influence the cellular degenerative process. Retinal macroglial cells, astrocytes, and Müller cells provide support for retinal neurons and are fundamental for maintaining normal retinal function. The aim of this study was to investigate the evolution of macroglial changes during retinal degeneration in P23H rats. Methods: Homozygous P23H line-3 rats aged from P18 to 18 months were used to study the evolution of the disease, and SD rats were used as controls. Immunolabeling with antibodies against GFAP, vimentin, and transducin were used to visualize macroglial cells and cone photoreceptors. Results: In P23H rats, increased GFAP labeling in Müller cells was observed as an early indicator of retinal gliosis. At 4 and 12 months of age, the apical processes of Müller cells in P23H rats clustered in firework-like structures, which were associated with ring-like shaped areas of cone degeneration in the outer nuclear layer. These structures were not observed at 16 months of age. The number of astrocytes was higher in P23H rats than in the SD matched controls at 4 and 12 months of age, supporting the idea of astrocyte proliferation. As the disease progressed, astrocytes exhibited a deteriorated morphology and marked hypertrophy. The increase in the complexity of the astrocytic processes correlated with greater connexin 43 expression and higher density of connexin 43 immunoreactive puncta within the ganglion cell layer (GCL) of P23H vs. SD rat retinas. Conclusions: In the P23H rat model of retinitis pigmentosa, the loss of photoreceptors triggers major changes in the number and morphology of glial cells affecting the inner retina

    Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae

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    Azole-resistant strains of Aspergillus fumigatus have been detected and the underlying molecular mechanisms of resistance characterized. Point mutations in the cyp51A gene have been proved to be related to azole resistance in A. fumigatus clinical strains and with different resistance profiles depending on the amino acid change (G54E, G54V, G54R, G54W, M220V, M220K, M220T, M220I). The aim of this work was to express A. fumigatus cyp51A genes in the yeast Saccharomyces cerevisiae in order to better assess the contribution of each independent amino acid substitution to resistance. A tetracycline regulatable system allowing repression of the endogenous essential ERG11 gene was used. The expression of Aspergillus cyp51A alleles could efficiently restore the absence of ERG11 in S. cerevisiae. In general, S. cerevisiae clones expressing. A. fumigatus cyp51A alleles from azole-resistant isolates showed higher MICs to all azoles tested than those expressing alleles from susceptible isolates. The azole susceptibility profiles obtained in S. cerevisiae upon expression of specific cyp51A alleles recapitulated susceptibility profiles observed from their A. fumigatus origins. In conclusion this work supports the concept that characteristics of specific A. fumigatus cyp51A alleles could be investigated in the heterologous host S. cerevisia

    Redesigning a case study for the assessment of ethical responsibility

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    [EN] This work presents the redesign of an activity (case study) that has been carried out over the last three years in the course Deontology and Professionalism for 2nd year students of the Informatics Engineering Degree at the Universitat Politecnica de Valencia (UPV) -Spain-. The aim of the activity is to encourage students to face ethical dilemmas that they may encounter in the exercise of their profession. Specifically, the case is about autonomous cars where decisions that must be taken imply a challenge, and even more when the programmers of the car deal with situations where human lives are endangered. The UPV has defined some general scoring rubrics in order to assess transversal competences of students. One of these rubrics deals with Ethics. Indicators included in this rubric are: The student: Becomes aware of other ways of seeing and perceiving things Critically accepts new perspectives, although this requires questioning your own perspective Differentiates facts from opinions in the arguments of other people Reflects on the consequences and effects (practical implications) that decisions and proposals have on people Recognizes the ethical and deontological aspects of the profession The case is introduced in a progressive way facilitating the development of the ethical competence and includes the required elements to assess the indicators established in the rubric. Thus, all the indicators proposed in the rubric can be evaluated by means of this activity. As a conclusion, the high degree of participation of the students in the activity is remarkable, which is on the one hand due to the transcendence of the theme and on the other hand because it is a very current topic closely linked to the computer science. Furthermore, the redesign of the case guided by the rubric allows an adequate evaluation.This research has been carried out under the project of innovation and educational improvement (PIME/A15) 'DAICE - Design of activities for the Innovation, Creativity and Entrepreneurship Competence' funded by the Universitat Politecnica de Valencia, and the Escola Tecnica Superior d'Enginyeria Informatica.Boza, A.; Fernández-Diego, M.; Cuenca, L.; Ruiz Font, L. (2017). Redesigning a case study for the assessment of ethical responsibility. INTED proceedings (Online). 6677-6682. doi:10.21125/inted.2017.1545S6677668

    Estudo da oferta e comercialização de repolho na CEAPE no período de 1999 a 2005.

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    Towards a framework for inter-enterprise architecture to boost collaborative networks

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    A complete Inter-Enterprise Architecture should be conformed to a framework, a methodology and a modelling language. In this sense, this paper proposes an initial Framework for Inter-Enterprise Architecture (FIEA), which organizes, stores, classifies and communicates in a conceptual level the elements of the Inter-Enterprise Architecture (IEA) and their relationships, ensuring their consistency and integrity. This FIEA provides a clear picture about the elements and perspectives that make up the collaborative network and their inter-relationships, supported for technology base on the Internet for its inter-operation.This research has been carried out for the project “Sistema de ayuda a la toma de decisiones ante decisiones no programadas en la planificación jerárquica de la producción (ADENPRO-PJP)” Ref. SP20120703 Universitat Politècnica de València.Vargas, A.; Boza García, A.; Cuenca, L.; Ortiz Bas, Á. (2013). Towards a framework for inter-enterprise architecture to boost collaborative networks. En On the Move to Meaningful Internet Systems: OTM 2013 Workshop. Springer Verlag (Germany). 179-188. https://doi.org/10.1007/978-3-642-41033-8_26S179188Cuenca, L., Boza, A., Ortiz, A.: Enterprise Architecture Framework with Early Business/ICT Alignment for Extended Enterprises. In: Ortiz, Á., Franco, R.D., Gasquet, P.G. (eds.) BASYS 2010. IFIP AICT, vol. 322, pp. 11–18. Springer, Heidelberg (2010a)Vargas, A., Boza, A., Cuenca, L., Sacala, I.: Inter-Enterprise Architecture and Internet of the Future. In: Camarinha-Matos, L.M., Tomic, S., Graça, P. (eds.) DoCEIS 2013. IFIP AICT, vol. 394, pp. 25–32. Springer, Heidelberg (2013)Camarinha-Matos, L., Afsarmanesh, H.: Collaborative networks: Reference Modeling. Media, Springer Science + Business (2008)European Commission European Society and Media: Dygital Business Ecosystems. Office for Official Publications of the European Communities, Luxembourg (2007)Future Internet Enterprise Systems (FInES) Cluster: FInES Research Roadmap 2025, http://cordis.europa.eu/Vargas, A., Boza, A., Cuenca, L., Ortiz, A.: The importance of strategic alignment in enterprise collaboration. In: Prado-Prado, J.C. (ed.) Annals of Industrial Engineering 2012, pp. 1–8. Springer, London (2013)Henderson, J., Venkatraman, N.: Strategic alignment: Leveraging information technology for transforming organizations. IBM Systems Journal 32(1), 472–484 (1993)Vargas, A., Boza, A., Cuenca, L.: Lograr la alineación estratégica de negocio y las tecnologías de la información a través de Arquitecturas Empresariales: Revisión de la Literatura. In: XV Congreso de Ingeniería de Organización, Cartagena-España, pp. 1061–1070 (2011a)ISO 15704: Industrial automation systems - Requirements for enterprise-reference architectures and methodologies (2000)Kosanke, K.: CIMOSA Primer on key concepts, purpose and business value. CIMOSA Association, http://cimosa.cnt.pl/Cuenca, L., Boza, A., Ortiz, A.: An enterprise engineering approach for the alignment of business and information technology strategy. International Journal of Computer Integrated Manufacturing 24(11), 974–992 (2011)Vernadat, F.: Enterprise modelling and integration: From fact modelling to Enterprise Interoperability (2003)Vargas, A., Boza, A., Cuenca, L.: Towards Interoperability Through Inter-Enterprise Collaboration Architectures. In: Meersman, R., Dillon, T., Herrero, P. (eds.) OTM-WS 2011. LNCS, vol. 7046, pp. 102–111. Springer, Heidelberg (2011)Plaza, J., Burgos, J., Carmona, E.: Measuring Stakeholder Integration: Knowledge, Interaction and Adaptational Behavior Dimensions. Journal of Business Ethics 93, 419–442 (2010)Camarinha-Matos, L.M., Afsarmanesh, H.: Collaborative networks: A new scientific discipline, pp. 439–452 (2005)Afsarmanesh, H., Msanjila, S.: Inter-organizational trust in VBEs. In: Camarinha-Matos, L.M., Afsarmanesh, H., Ollus, M. (eds.) Methods and Tools for Collaborative Networked Organizations. Springer (2008)Mehandjiev, N., Grefen, P.: Dynamic business process formation for instant virtual enterprises, London (2010)Kosanke, K., Vernadat, F., Zelm, M.: CIMOSA: enterprise engineering and integration. Computers in Industry 40, 83–97 (1999)Chen, D., Vallespir, B., Doumeingts, G.: GRAI integrated methodology and its mapping onto generic enterprise reference architecture and methodology. Computers in Industry 33, 387–394 (1997)IFIP: GERAM: Generalised Enterprise Reference Architecture and Methodology. In: International Federation for Information Processing, http://dl.ifip.org/index.php/index/indexOrtiz, A., Lario, F., Ros, L.: Enterprise Integration—Business Processes Integrated Management: a proposal for a methodology to develop Enterprise Integration Programs. Computers in Industry 40, 155–171 (1999)Cuenca, L., Ortiz, A., Boza, A.: Business and IS/IT strategic alignment framework. In: Camarinha-Matos, L.M., Pereira, P., Ribeiro, L. (eds.) DoCEIS 2010. IFIP AICT, vol. 314, pp. 24–31. Springer, Heidelberg (2010b)THE OPEN GROUP: TOGAF, http://www.opengroup.org/togaf/Vesterager, J., T{\o}lle, M., Bernus, P.: VERA: Virtual Enterprise Reference Architecture. In: GMNBook, GLOBEMEN Final Plenary (2002)Chalmeta, R., Grangel, R.: ARDIN extension for virtual enterprise integration. The Journal of Systems and Software 67 (2003

    Towards the development of the framework for inter sensing enterprise architecture

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    [EN] Inter-enterprise architecture (IEA) is a new concept that seeks to apply the tools and methodologies of enterprise architecture (EA) in a collaborative context, in order to model collaborative organizations in an inclusive manner. According to the main enterprise architectures proposed to this point, an EA should be conformed at least for a framework, a methodology and a modelling language. Sensing enterprise (SE) is an attribute of an enterprise or a network that allows it to react to business stimuli originating on the Internet. These fields have come into focus recently, and there is not evidence of the use of IEA for modelling a SE, while finding an interesting gap to work on. Thus, this paper proposes an initial framework for inter sensing enterprise architecture (FISEA), which seeks to classify, organize, store and communicate, at the conceptual level, all the elements for inter-sensing enterprise architectures and their relationships, ensuring their consistency and integrity. This FISEA provides a clear idea about the elements and views that create collaborative network and their inter-relationships, based on the support of Future Internet.This work was supported by the European Commission FP7 UNITE Project, through its Secondment Programme and the Universitat Politecnica de Valencia ADENPRO-PJP project (ref. SP20120703).Vargas, A.; Cuenca, L.; Boza, A.; Sacala, I.; Moisescu, M. (2016). Towards the development of the framework for inter sensing enterprise architecture. Journal of Intelligent Manufacturing. 27(1):55-72. https://doi.org/10.1007/s10845-014-0901-zS5572271Adaba, G., Rusu, L., & Mekawy, M. (2010). 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International Transactions in Operational Research, 19(5), 633–657.Boza, A., Cuenca, L., Poler, R., Michaelides, Z., & Systems, Enterprise Information. (2014). The interoperability force in the ERP field. Enterprise Information Systems,. doi: 10.1080/17517575.2013.866697Camarinha-Matos, L., & Afsarmanesh, H. (2005). Collaborative networks: A new scientific discipline. Journal of Intelligent Manufacturing, 16(4–5), 439–452.Camarinha-Matos, L., & Afsarmanesh, H. (2008). Collaborative networks: Reference modeling. New York: Springer.Camarinha-Matos, L., Afsarmanesh, H., & Ollus, M. (2008). ECOLEAD and CNO base concepts. In L. M. Camarinha-Matos, H. Afsarmanesh, & M. Ollus (Eds.), Methods and tools for collaborative networked organizations (pp. 35–68). New York: Springer.Chalmeta, R., & Grangel, R. (2003). ARDIN extension for virtual enterprise integration. The Journal of Systems and Software, 67(3), 141–152.Chen, D., Vallespir, B., & Doumeingts, G. (1997). GRAI integrated methodology and its mapping onto generic enterprise reference architecture and methodology. Computers in Industry, 33(2), 387–394.Choi, Y., Kang, D., Chae, H., & Kim, K. (2008). An enterprise architecture framework for collaboration of virtual enterprise chains. The International Journal of Advanced Manufacturing Technology, 35(11–12), 1065–1078.CIMOSA Asociation. (1996). CIMOSA Primer on key concepts, purpose and business value.Council of Supply Chain Management Professionals CSCMP. (2010). CSCMP. Glosary of terms. from http://cscmp.org/resources-research/glossary-terms . Accessed 9 February 2013Coutinho, C., Cretan, A., Ferreira, C., Ghodous, P., & Jardim-Goncalves, R. (2014). Service-based negotiation for advanced collaboration in enterprise networks. Journal of Intelligent Manufacturing,. doi: 10.1007/s10845-013-0857-4Cuenca, L. (2009). Marco arquitectónico para la propuesta IE-GIP. Extensión de la arquitectura CIMOSA. Aplicación a una empresa del sector cerámico. Tesis Doctoral Universidad Politecnica de Valencia.Cuenca, L., Boza, A., & Ortiz, A. (2011). An enterprise engineering approach for the alignment of business and information technology strategy. International Journal of Computer Integrated Manufacturing, 24(11), 974–992.Cuenca, L., Ortiz, A., & Boza, A. (2005). Arquitectura de Empresa. Visión General. Gijón: IX Congreso de Ingeniería de Organización.Dong, X., Liu, Q., & Yin, D. (2008). Business performance, business strategy, and information system strategic alignment: An empirical study on Chinese firms. Tsinghua Science and Technology, 13(3), 348–354.Ermilova, E., & Afsarmanesh, H. (2007). Modeling and management of profiles and competencies in VBEs. Journal of Intelligent Manufacturing, 18(5), 561–586.Estimali, H., Gardesh, H., & Sikari, S. (2010). Validating ITIL maturity to strategic business-IT alignment. In 2nd International conference on computer technology and development (ICCTD 2010).European Commission European Society and Media. (2007). Dygital Business Ecosystems. In F. Nachira, P. Dini, A. Nicolai, M. Le Louarn, & L. Rivera (Eds.). http://www.digital-ecosystems.org/book/ . Luxembourg: Office for Official Publications of the European Communities. Accessed 15 October 2012Executive Branch of the U.S. Federal Government. (2012). A Common Approach to Federal Enterprise Architecture. The White House. http://www.whitehouse.gov/sites/default/files/omb/assets/egov_docs/common_approach_to_federal_ea.pdf . Accessed 13 August 2013Franco, R., Gomez, P., Ortiz, A., & Navarro, R. (2012). Integrated approach for interoperability in collaborative networs and service-based ecosystems. In R. Poler, G. Doumeingts, B. Katzy, & R. Chalmeta (Eds.), Enterpise interoperability V (pp. 329–339). London: Springer.Force, I. F. I. P.-I. F. A. C. Task. (1998). GERAM: Generalised enterprise reference architecture and methodology. International Federation for Information Processing, 1(2), 30.Future Internet Enterprise Systems (FInES) Cluster. (2012). FInES Research Roadmap 2025. From http://cordis.europa.eu/fp7/ict/enet/documents/fines-research-roadmap-v30_en.pdf . Accessed 13 October 2013Henderson, J., & Venkatraman, N. (1993). Strategic alignment: Leveraging information technology for transforming organizations. IBM Systems Journal, 32(1), 472–484.Hu, Q., & Huang, D. (2006). Using the balanced scorecard to achieve sustained IT-business alignment: A case study. Communications of the Association for Information Systems, 17, 181–204.ISO 15704. (2000). Industrial automation systems–Requirements for enterprise-reference architectures and methodologies.ISO/CEN 19439. (2006). Enterprise integration–Framework for enterprise modelling.Kilger, C., Reuter, B., & Stadtler, H. (2008). Collaborative planning. In H. Stadtler & C. Kilger (Eds.), Supply chain management and advanced planning-concepts, models software and case studies (pp. 263–284). Berlin, Heidelberg: Springer.Kosanke, K., Vernadat, F., & Zelm, M. (1999). CIMOSA: Enterprise engineering and integration. Computers in Industry, 40(2), 83– 97.Lankhorst, M. (2009). Enterprise architecture at work: Modelling, communication and analysis. New York: Springer.Luftman, J. (2004). Assessing business-IT alignment maturity. Communications of the Association for Information Systems, 4, 99.Maes, R. (1999). Reconsidering information management through a generic framework. Amsterdam: Universiteit van Amsterdam, Department of Accountancy & Information Management.Mehandjiev, N., & Grefen, P. (2010). Dynamic business process formation for instant virtual enterprises. London.Mekawy, M., Rusu, L., & Ahmed, N. (2009). Business and IT alignment: An evaluation of strategic alignment models. In best practices for the knowledge society. 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Measuring stakeholder integration: Knowledge, interaction and adaptational behavior dimensions. Journal of Business Ethics, 93, 419–442.Romero, D., Galeano, N., & Molina, A. (2010). Virtual organisation breeding environments value system and its elements. Journal of Intelligent Manufacturing, 21(3), 267–286.Sacala, I., Moisescu, M., & Repta, D. (2013). Towards the development of the future internet based enterprise in the context of cyber-physical systems. In 2013 19th International conference on control systems and computer science (CSCS), (pp. 405–412).Santana, R., Daneva, M., van Eck, P., & Wieringa, R. (2008). Towards a business-IT aligned maturity model for collaborative networked organizations. In 12th International conference on advanced information systems engineering.Schekkerman, J. (2004). Enterprise architecture validation. Achieving business-aligned and validated entreprise architectures. 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